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《医学前沿(英文)》 2013年 第7卷 第3期 页码 306-315 doi: 10.1007/s11684-013-0279-x
Allogeneic hematopoietic stem cell transplantation (HSCT) is one of the most effective options for hematological malignancies, and human leukocyte antigen-partially matched related donors (PMRDs) are a valuable option for HSCT. Several protocols (with or without ex vivo T-cell depletion (TCD)) have been established worldwide. TCD including CD34+positive selection and CD3/CD19 depletion has successfully overcome the human leukocyte antigen disparity. However, TCD is associated with prolonged immune deficiencies, increased risks of infectious complications, and high transplantation-related mortality. PMRD HSCT without ex vivo TCD is well developed, and numerous patients have benefitted from it. Here, we review the literature on PMRD HSCT.
关键词: partially matched related donor hematopoietic stem cell transplantation allogeneic
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《医学前沿(英文)》 2018年 第12卷 第2期 页码 153-163 doi: 10.1007/s11684-017-0548-1
To establish optimal reference values for recovered immune cell subsets, we prospectively investigated post-transplant immune reconstitution (IR) in 144 patients who received allogeneic stem cell transplantation (allo-SCT) and without showing any of the following events: poor graft function, grades II?IV acute graft-versus-host disease (GVHD), serious chronic GVHD, serious bacterial infection, invasive fungal infection, or relapse or death in the first year after transplantation. IR was rapid in monocytes, intermediate in lymphocytes, CD3+ T cells, CD8+ T cells, and CD19+ B cells, and very slow in CD4+ T cells in the entire patient cohort. Immune recovery was generally faster under HLA-matched sibling donor transplantation than under haploidentical transplantation. Results suggest that patients with an IR comparable to the reference values display superior survival, and the levels of recovery in immune cells need not reach those in healthy donor in the first year after transplantation. We suggest that data from this recipient cohort should be used as reference values for post-transplant immune cell counts in patients receiving HSCT.
关键词: immune reconstitution hematopoietic stem cell transplantation event-free patients reference range
《环境科学与工程前沿(英文)》 2022年 第16卷 第7期 doi: 10.1007/s11783-021-1517-0
• Fate of microplastics in integrated membrane system for water reuse was investigated.
关键词: Water reclamation Integrated membrane system Microplastics Removal Coastal zone
The influence of brain death on donor liver and the potential mechanisms of protective intervention
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《医学前沿(英文)》 2011年 第5卷 第1期 页码 8-14 doi: 10.1007/s11684-011-0109-y
Brain-dead donors have become one of the main sources of organs for transplantation in Western countries. The quality of donor organs is closely related to the outcome of the transplantation. Experimental studies have confirmed the inferior graft survival of livers from brain-dead donors compared with those from living donors. Studies conducted in the past 10 years have shown that brain death is associated with effects on the decreased donor organ quality. However, whether the decrease in the viability of donor organs is caused by brain death or by the events before and after brain death remains uncertain. The purpose of this review is to introduce the advances and controversies regarding the influence of brain death on the viability of donor livers and to summarize the mechanisms of the different protective interventions for donor livers.
关键词: brain death donor liver
《机械工程前沿(英文)》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0695-1
关键词: translational parallel mechanism single loop multiple driving system workspace analysis singularity
Regulation of radicals by hydrogen-donor solvent in direct coal liquefaction
《化学科学与工程前沿(英文)》 2022年 第16卷 第12期 页码 1689-1699 doi: 10.1007/s11705-022-2186-7
关键词: direct coal liquefaction hydrogen-donor solvent induced pyrolysis radical mechanism density functional theory calculations
Enhanced photoelectrochemical water splitting with a donor-acceptor polyimide
《能源前沿(英文)》 doi: 10.1007/s11708-023-0910-8
关键词: polyimide (PI) film photoelectrochemistry band structure engineering aromatic unit
Performance enhancement of partially shaded solar PV array using novel shade dispersion technique
Namani RAKESH,T. Venkata MADHAVARAM
《能源前沿(英文)》 2016年 第10卷 第2期 页码 227-239 doi: 10.1007/s11708-016-0405-y
关键词: photovoltaic cells mismatch loss shading patterns partial shading magic square power enhancement global peaks and total cross tied (TCT)
《医学前沿(英文)》 2021年 第15卷 第5期 页码 728-739 doi: 10.1007/s11684-021-0833-x
关键词: second hematopoietic stem cell transplantation acute leukemia relapse chemotherapy modified donor lymphocyte infusion
Yixiang REN, Zhenhui YE, Yining CHEN, Xiaohong JIANG, Guanghua SONG
《信息与电子工程前沿(英文)》 2023年 第24卷 第3期 页码 480-480 doi: 10.1631/FITEE.22e0073
Meng Lv, Yingjun Chang, Xiaojun Huang
《医学前沿(英文)》 2019年 第13卷 第1期 页码 45-56 doi: 10.1007/s11684-017-0595-7
关键词: haploidentical hematopoietic stem cell transplantation conditioning graft-versus-host disease relapse infection donor selection
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《医学前沿(英文)》 2017年 第11卷 第4期 页码 563-569 doi: 10.1007/s11684-017-0535-6
The superiority of the cumulative outcomes of day 5/6 embryo transfer to those of day 2/3 embryo transfer in infertile couples has been debated. This retrospective study included data collected from 1051 patients from July 2011 to June 2014. Multiple maternal baseline covariates were subjected to propensity score matching analysis, and each day 5/6 group woman was matched to one day 2/3 group woman. A systematic meta-analysis was conducted to validate the results. After matching was completed, 217 patients on the day 2/3 group were matched with those on the day 5/6 group, and no significant differences in the baseline characteristics were observed between the two groups. The cumulative pregnancy rate (57.14% vs. 53.46%, OR 1.16, 95% CI 0.79–1.70) and cumulative live birth rate (53.00% vs. 49.77%, OR 1.14, 95% CI 0.78–1.66) of day 5/6 embryo transfers were higher than those of day 2/3 embryo transfers, but this difference was not significant. The mean cycles per live birth and mean days per live birth in the day 5/6 group were significantly lower than those in the day 2/3 group. This study demonstrated that day 5/6 embryo transfer is a more cost-effective and time-efficient policy than day 2/3 embryo transfer to produce a live baby.
关键词: blastocyst embryo transfer cumulative pregnancy rate cumulative live birth rate IVF
Zhen-Pei WANG, Zhifeng XIE, Leong Hien POH
《机械工程前沿(英文)》 2020年 第15卷 第2期 页码 279-293 doi: 10.1007/s11465-019-0575-5
关键词: isogeometric shape optimization design-dependent boundary condition transient heat conduction implicit time integration adjoint method
Projections of heat-related excess mortality in China due to climate change, population and aging
《环境科学与工程前沿(英文)》 2023年 第17卷 第11期 doi: 10.1007/s11783-023-1732-y
● Four scenarios were used to project heat-related excess mortality in China.
Effects and mechanisms of acupuncture on women related health
《医学前沿(英文)》 doi: 10.1007/s11684-023-1051-5
标题 作者 时间 类型 操作
Advancement of human leukocyte antigen-partially matched related hematopoietic stem cell transplantation
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期刊论文
event-free patients receiving haploidentical allografts and those receiving human leukocyte antigen-matchedsibling donor allografts
null
期刊论文
Fate of microplastics in a coastal wastewater treatment plant: Microfibers could partially break through
期刊论文
The influence of brain death on donor liver and the potential mechanisms of protective intervention
null
期刊论文
Design and analysis of partially decoupled translational parallel mechanisms with single-loop structures
期刊论文
Performance enhancement of partially shaded solar PV array using novel shade dispersion technique
Namani RAKESH,T. Venkata MADHAVARAM
期刊论文
used as a salvage option for patients with relapsed acute leukemia post-chemotherapy plus modified donor
期刊论文
Erratum to: Soft-HGRNs: soft hierarchical graph recurrent networks for multi-agent partially observable
Yixiang REN, Zhenhui YE, Yining CHEN, Xiaohong JIANG, Guanghua SONG
期刊论文
Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic
Meng Lv, Yingjun Chang, Xiaojun Huang
期刊论文
Propensity score-matched study and meta-analysis of cumulative outcomes of day 2/3 versus day 5/6 embryo
null
期刊论文
An isogeometric numerical study of partially and fully implicit schemes for transient adjoint shape sensitivity
Zhen-Pei WANG, Zhifeng XIE, Leong Hien POH
期刊论文
Projections of heat-related excess mortality in China due to climate change, population and aging
期刊论文